Description
A triterpene; inhibits the activity of HIV-1 protease (IC50 = 70 µM), as well as reduces 5α-reductase activity by 32% at 667 µM; inhibits proliferation, colony formation, invasion, and migration of MDA-MB-231 human breast cancer cells at 25 and 50 µM; reduces hepatocyte necrosis and increases in hepatic TNF-α and IL-6 levels in a mouse model of LPS/D-galactosamine-induced acute liver injury at 5 mg/kg